2025
Stefanowska, A., Czapczyński, M., Koprowski, P., Szewczyk, A., Krysiński, P. Time-resolved electromechanical and conductive behavior of nanostructured bilayers tethered to the surface of the electrode with incorporated channel proteins and peptides (2025) Bioelectrochemistry, Volume 162, ,108848, https://doi.org/10.1016/j.bioelechem.2024.108848.
2024
Kravenska Y., Koprowski P., Nieznanska H., Nieznanski K. Prion protein prevents the inhibition of large-conductance calcium-activated potassium channel by Tau peptide K18 oligomers (2024) Biochem Biophys Res Commun. 734:150793. doi: 10.1016/j.bbrc.2024.150793
Dżugaj, A., Barańska, J., Szewczyk, A. Jakub Karol Parnas. Odkrycie glikolizy – szlaku Embdena-Meyerhofa-Parnasa (2024) NAUKA 2/2024, 95–104, DOI: 10.24425/nauka.2024.151208
Barańska, J., Dżugaj, A., Szewczyk, A. Professor Jakub Karol Parnas: 140th birth anniversary [Profesor Jakub Karol Parnas: 140 rocznica urodzin] (2024) Postepy biochemii, 70 (2), pp. 279-288. DOI: 10.18388/pb.2021_524
Ferraboschi, I., Ovcar, J., Vygranenko, K.V., Yu, S., Minervino, A., Wrzosek, A., Szewczyk, A., Rozza, R., Magistrato, A., Belfield, K.D., Gryko, D.T., Grisanti, L., Sissa, C. Neutral rhodol-based dyes expressing localization in mitochondria (2024) Organic and Biomolecular Chemistry, 22 (29), pp. 5886-5890.
DOI: 10.1039/d4ob00252k
Tasior, M., Vakuliuk, O., Wrzosek, A., Vullev, V.I., Szewczyk, A., Jacquemin, D., Gryko, D.T. Quadrupolar, Highly Polarized Dyes: Emission Dependence on Viscosity and Selective Mitochondria Staining (2024) ACS Organic and Inorganic Au, 4 (2), pp. 248-257. DOI: 10.1021/acsorginorgau.3c00035
Lewandowska, J., Kalenik, B., Wrzosek, A., Szewczyk, A. Redox Regulation of Mitochondrial Potassium Channels Activity (2024) Antioxidants, 13 (4), art. no. 434, . DOI: 10.3390/antiox13040434
Krajewska, M., Możajew, M., Filipek, S., Koprowski, P. Interaction of ROMK2 channel with lipid kinases DGKE and AGK: Potential channel activation by localized anionic lipid synthesis (2024) BBA 1869 (2), 159443 DOI: 10.1016/j.bbalip.2023.159443
Maliszewska-Olejniczak K, Pytlak, K., Dabrowska, A., Zochowska, M., Hoser, J., Lukasiak, A., Zajac, M., Kulawiak, B., Bednarczyk, P. Deficiency of the BKCa potassium channel displayed significant implications for the physiology of the human bronchial epithelium (2024) Mitochondrion, 76, 101880.
DOI: 10.1016/j.mito.2024.101880
Badaro, J. S. A., Wrzosek, A., Morawski, O., Szewczyk, A., Deperasińska, I., Gryko, D.T. Strongly fluorescent indolizine-based coumarin analogs (2024) Organic Chemistry Frontiers, DOI: 10.1039/d4qo01216j
Szewczyk, A. Understanding mitochondrial potassium channels: 33 years after discovery (2024) Acta Biochimica Polonica, 71, art. no. 13126 DOI: 10.3389/abp.2024.13126
2023
Bischof Helmut, Maier Selina, Koprowski Piotr, Kulawiak Bogusz, Burgstaller Sandra, Jasińska Joanna, Serafimov Kristian, Gross Dominic, Schroth Werner, Matt Lucas, Juarez Lopez David Arturo, Bonzheim Irina, Büttner Florian A., Fend Falko, Schwab Matthias, Birkenfeld Andreas L., Malli Roland, Lämmerhofer Michael, Bednarczyk Piotr, Szewczyk Adam, Lukowski Robert (2023) mitoBKCa is functionally expressed in murine and human breast cancer cells and promotes metabolic reprogramming eLife 12:RP92511 DOI: 10.7554/eLife.92511.1
Tasior, M., Vakuliuk, O., Wrzosek, A., Vullev, V.I., Szewczyk, A., Jacquemin D., Gryko, D.T. Quadrupolar, highly polarized dyes: emission dependence on viscosity and selective mitochondria staining. (2023) ACS Organic & Inorganic Au. DOI: 10.1021/acsorginorgau.3c00035
Głuchowska, A., Kalenik, B., Kulawiak, B., Wrzosek, A., Szewczyk, A., Bednarczyk, P., Mosieniak, G. Lack of activity of the mitochondrial large-conductance calcium-regulated potassium channels in senescent vascular smooth muscle cells. (2023) Mechanisms of Ageing and Development, 215, art. no. 111871, . DOI: 10.1016/j.mad.2023.111871
Kulawiak, B., Żochowska, M., Bednarczyk, P., Galuba, A., Stroud, D.A., Szewczyk, A. Loss of the large conductance calcium-activated potassium channel causes an increase in mitochondrial reactive oxygen species in glioblastoma cells (2023) Pflugers Archiv – European Journal of Physiology, 475 (9), pp. 1045-1060. DOI: 10.1007/s00424-023-02833-9
Stefanowska, A., Koprowski, P., Bednarczyk, P., Szewczyk, A., Krysinski, P. Electrochemical studies of the mitochondrial ROMK2 potassium channel activity reconstituted into the free-standing and tethered bilayer lipid membranes (2023) Bioelectrochemistry, 151, art. no. 108372, . DOI: 10.1016/j.bioelechem.2023.108372
Szabo, I., Szewczyk, A. Mitochondrial Ion Channels (2023) Annual Review of Biophysics, 52, pp. 229-254. DOI: 10.1146/annurev-biophys-092622-094853
Kampa, R.P., Sȩk, A., Bednarczyk, P., Szewczyk, A., Calderone, V., Testai, L. Flavonoids as new regulators of mitochondrial potassium channels: Contribution to cardioprotection (2023) Journal of Pharmacy and Pharmacology, 75 (4), pp. 466-481. DOI: 10.1093/jpp/rgac093
Krajewska, M., Szewczyk, A., Kulawiak, B., Koprowski, P. Pharmacological Characterization of a Recombinant Mitochondrial ROMK2 Potassium Channel Expressed in Bacteria and Reconstituted in Planar Lipid Bilayers (2023) Membranes, 13 (3), art. no. 360, DOI: 10.3390/membranes13030360
2022
Wrzosek, A., Gałecka, S., Żochowska, M., Olszewska, A., & Kulawiak, B. (2022). Alternative Targets for Modulators of Mitochondrial Potassium Channels. Molecules, 27(1), 299.
Olszewska, A.M., Sieradzan, A.K., Bednarczyk, P., Szewczyk, A., Żmijewski, M.A. Mitochondrial potassium channels: A novel calcitriol target (2022) Cellular and Molecular Biology Letters, 27 (1), art. no. 3, DOI: 10.1186/s11658-021-00299-0
Walewska, A., Szewczyk, A., Koprowski, P. External Hemin as an Inhibitor of Mitochondrial Large-Conductance Calcium-Activated Potassium Channel Activity (2022) International Journal of Molecular Sciences, 23 (21), art. no. 13391, DOI: 10.3390/ijms232113391
Kampa, R.P., Flori, L., Sęk, A., Spezzini, J., Brogi, S., Szewczyk, A., Calderone, V., Bednarczyk, P., Testai, L. Luteolin-Induced Activation of Mitochondrial BKCa Channels: Undisclosed Mechanism of Cytoprotection (2022) Antioxidants, 11 (10), art. no. 1892, DOI: 10.3390/antiox11101892
Kumar, G.D., Banasiewicz, M., Wrzosek, A., O’Mari, O., Zochowska, M., Vullev, V.I., Jacquemin, D., Szewczyk, A., Gryko, D.T. A sensitive zinc probe operating via enhancement of excited-state intramolecular charge transfer (2022) Organic and Biomolecular Chemistry, 20 (37), pp. 7439-7447. DOI: 10.1039/d2ob01296k
Kampa, R.P., Gliździńska, A., Szewczyk, A., Bednarczyk, P., Filipek, S. Flavonoid quercetin abolish paxilline inhibition of the mitochondrial BKCa channel (2022) Mitochondrion, 65, pp. 23-32. DOI: 10.1016/j.mito.2022.04.005
Kulawiak, B., Szewczyk, A. Current Challenges of Mitochondrial Potassium Channel Research (2022) Frontiers in Physiology, 13, art. no. 907015, DOI: 10.3389/fphys.2022.907015
Walewska, A., Szewczyk, A., Krajewska, M., Koprowski, P. Targeting Mitochondrial Large-Conductance Calcium-Activated Potassium Channel by Hydrogen Sulfide via Heme-Binding Site (2022) Journal of Pharmacology and Experimental Therapeutics, 381 (2), pp. 137-150. DOI: 10.1124/jpet.121.001017
Buta, A., Nazaruk, E., Dziubak, D., Szewczyk, A., Bilewicz, R. Properties of electrode-supported lipid cubic mesophase films with embedded gramicidin A: structure and ion-transport studies (2022) Bioelectrochemistry, 144, art. no. 108042, DOI: 10.1016/j.bioelechem.2021.108042
Kumar, G.D., Banasiewicz, M., Wrzosek, A., Kampa, R.P., Bousquet, M.H.E., Kusy, D., Jacquemin, D., Szewczyk, A., Gryko, D.T. Probing the flux of mitochondrial potassium using an azacrown-diketopyrrolopyrrole based highly sensitive probe (2022) Chemical Communications, 58 (28), pp. 4500-4503. DOI: 10.1039/d2cc00324d
Walewska, A., Krajewska, M., Stefanowska, A., Buta, A., Bilewicz, R., Krysiński, P., Bednarczyk, P., Koprowski, P., Szewczyk, A. Methods of Measuring Mitochondrial Potassium Channels: A Critical Assessment (2022) International Journal of Molecular Sciences, 23 (3), art. no. 1210, DOI: 10.3390/ijms23031210
2021
Gałecka, S*., Kulawiak, B.*, Bednarczyk, P., Singh, H., Szewczyk, A. Single channel properties of mitochondrial large conductance potassium channel formed by BK-VEDEC splice variant (2021) Scientific Reports, 11 (1), art. no. 10925, DOI: 10.1038/s41598-021-90465-3
Kampa, R.P., Sęk, A., Szewczyk, A., Bednarczyk, P. Cytoprotective effects of the flavonoid quercetin by activating mitochondrial BKCa channels in endothelial cells. (2021) Biomedicine and Pharmacotherapy, 142, art. no. 112039, DOI: 10.1016/j.biopha.2021.112039
Vygranenko, K.V., Poronik, Y.M., Wrzosek, A., Szewczyk, A., Gryko, D.T. Red emissive sulfone-rhodols as mitochondrial imaging agents (2021) Chemical Communications, 57 (63), pp. 7782-7785. DOI: 10.1039/d1cc02687a
Kulawiak, B., Bednarczyk, P., Szewczyk, A. Multidimensional regulation of cardiac mitochondrial potassium channels (2021) Cells, 10 (6), art. no. 1554, DOI: 10.3390/cells10061554
Sek, A., Kampa, R.P., Kulawiak, B., Szewczyk, A., Bednarczyk, P. Identification of the large‐conductance ca2+‐regulated potassium channel in mitochondria of human bronchial epithelial cells (2021) Molecules, 26 (11), art. no. 3233, DOI: 10.3390/molecules26113233
Kozon, D., Bednarczyk, P., Szewczyk, A., Jańczewski, D. Regulation of Lipid Bilayer Ion Permeability by Antibacterial Polymethyloxazoline-Polyethyleneimine Copolymers (2021) ChemBioChem, 22 (6), pp. 1020-1029. DOI: 10.1002/cbic.202000656
2020
Kravenska, Y., Nieznanska, H., Nieznanski, K., Lukyanetz, E., Szewczyk, A., Koprowski, P. The monomers, oligomers, and fibrils of amyloid-β inhibit the activity of mitoBKCa channels by a membrane-mediated mechanism (2020) Biochimica et Biophysica Acta – Biomembranes, 1862 (9), art. no. 183337 DOI: 10.1016/j.bbamem.2020.183337
Rotko, D., Bednarczyk, P., Koprowski, P., Kunz, W.S., Szewczyk, A., Kulawiak, B. Heme is required for carbon monoxide activation of mitochondrial BKCa channel (2020) European Journal of Pharmacology, 881, art. no. 173191, DOI: 10.1016/j.ejphar.2020.173191
Wrzosek, A., Augustynek, B., Żochowska, M., Szewczyk, A. Mitochondrial potassium channels as druggable targets (2020) Biomolecules, 10 (8), art. no. 1200, pp. 1-19. DOI: 10.3390/biom10081200
Rotko, D., Kunz, W.S., Szewczyk, A., Kulawiak, B. Signaling pathways targeting mitochondrial potassium channels (2020) International Journal of Biochemistry and Cell Biology, 125, art. no. 105792, DOI: 10.1016/j.biocel.2020.105792
Kicinska, A., Kampa, R.P., Daniluk, J., Sek, A., Jarmuszkiewicz, W., Szewczyk, A., Bednarczyk, P. Regulation of the mitochondrial BKCa channel by the citrus flavonoid naringenin as a potential means of preventing cell damage (2020) Molecules, 25 (13), art. no. 3010, DOI: 10.3390/molecules25133010
2019
Laskowski, M., Augustynek, B., Bednarczyk, P., Żochowska, M., Kalisz, J., O’rourke, B., Szewczyk, A., Kulawiak, B. Single-channel properties of the ROMK-pore-forming subunit of the mitochondrial ATP-sensitive potassium channel (2019) International Journal of Molecular Sciences, 20 (21), art. no. 5323, . DOI: 10.3390/ijms20215323
Ponnalagu, D., Hussain, A.T., Thanawala, R., Meka, J., Bednarczyk, P., Feng, Y., Szewczyk, A., GururajaRao, S., Bopassa, J.C., Khan, M., Singh, H. Chloride channel blocker IAA-94 increases myocardial infarction by reducing calcium retention capacity of the cardiac mitochondria (2019) Life Sciences, 235, art. no. 116841 DOI: 10.1016/j.lfs.2019.116841
Rao, S.G., Bednarczyk, P., Towheed, A., Shah, K., Karekar, P., Ponnalagu, D., Jensen, H.N., Addya, S., Reyes, B.A.S., Van Bockstaele, E.J., Szewczyk, A., Wallace, D.C., Singh, H. BKCa (Slo) channel regulates mitochondrial function and lifespan in drosophila melanogaster (2019) Cells, 8 (9), art. no. 945, . DOI: 10.3390/cells8090945
Kampa, R.P., Kicinska, A., Jarmuszkiewicz, W., Pasikowska-Piwko, M., Dolegowska, B., Debowska, R., Szewczyk, A., Bednarczyk, P. Naringenin as an opener of mitochondrial potassium channels in dermal fibroblasts (2019) Experimental Dermatology, 28 (5), pp. 543-550. DOI: 10.1111/exd.13903
Jarmuszkiewicz, W., Szewczyk, A. Energy-dissipating hub in muscle mitochondria: Potassium channels and uncoupling proteins (2019) Archives of Biochemistry and Biophysics, 664, pp. 102-109. DOI: 10.1016/j.abb.2019.01.036
2018
Walewska, A., Szewczyk, A., Koprowski, P. Gas signaling molecules and mitochondrial potassium channels (2018) International Journal of Molecular Sciences, 19 (10), art. no. 3227, . DOI: 10.3390/ijms19103227
Walewska, A., Kulawiak, B., Szewczyk, A., Koprowski, P. Mechanosensitivity of mitochondrial large-conductance calcium-activated potassium channels (2018) Biochimica et Biophysica Acta – Bioenergetics, 1859 (9), pp. 797-805. DOI: 10.1016/j.bbabio.2018.05.006
Bednarczyk, P., Kicinska, A., Laskowski, M., Kulawiak, B., Kampa, R., Walewska, A., Krajewska, M., Jarmuszkiewicz, W., Szewczyk, A. Evidence for a mitochondrial ATP-regulated potassium channel in human dermal fibroblasts (2018) Biochimica et Biophysica Acta – Bioenergetics, 1859 (5), pp. 309-318. DOI: 10.1016/j.bbabio.2018.02.005
Poronik, Y.M., Bernaś, T., Wrzosek, A., Banasiewicz, M., Szewczyk, A., Gryko, D.T. One-Photon and Two-Photon Mitochondrial Fluorescent Probes Based on a Rhodol Chromophore (2018) Asian Journal of Organic Chemistry, 7 (2), pp. 411-415. DOI: 10.1002/ajoc.201700600
Augustynek, B., Koprowski, P., Rotko, D., Kunz, W.S., Szewczyk, A., Kulawiak, B. Mitochondrial BK channel openers CGS7181 and CGS7184 exhibit cytotoxic properties (2018) International Journal of Molecular Sciences, 19 (2), art. no. 353, DOI: 10.3390/ijms19020353
2017
Frankenreiter, S., Bednarczyk, P., Kniess, A., Bork, N.I., Straubinger, J., Koprowski, P., Wrzosek, A., Mohr, E., Logan, A., Murphy, M.P., Gawaz, M., Krieg, T., Szewczyk, A., Nikolaev, V.O., Ruth, P., Lukowski, R. cGMP-Elevating Compounds and Ischemic Conditioning Provide Cardioprotection Against Ischemia and Reperfusion Injury via Cardiomyocyte-Specific BK Channels (2017) Circulation, 136 (24), pp. 2337-2355. DOI: 10.1161/CIRCULATIONAHA.117.028723
Augustynek, B., Kunz, W.S., Szewczyk, A. Guide to the pharmacology of mitochondrial potassium channels (2017) Handbook of Experimental Pharmacology, 240, DOI: 10.1007/164_2016_79
2016
Laskowski, M., Augustynek, B., Kulawiak, B., Koprowski, P., Bednarczyk, P., Jarmuszkiewicz, W., Szewczyk, A. What do we not know about mitochondrial potassium channels? (2016) Biochimica et Biophysica Acta – Bioenergetics, 1857 (8), pp. 1247-1257. DOI: 10.1016/j.bbabio.2016.03.007
Kicinska, A., Augustynek, B., Kulawiak, B., Jarmuszkiewicz, W., Szewczyk, A., Bednarczyk, P. A large-conductance calcium-regulated K + channel in human dermal fibroblast mitochondria (2016) Biochemical Journal, 473 (23), pp. 4457-4471. DOI: 10.1042/BCJ20160732
Łukasiak, A., Skup, A., Chlopicki, S., Łomnicka, M., Kaczara, P., Proniewski, B., Szewczyk, A., Wrzosek, A. SERCA, complex I of the respiratory chain and ATP-synthase inhibition are involved in pleiotropic effects of NS1619 on endothelial cells (2016) European Journal of Pharmacology, 786, pp. 137-147. DOI: 10.1016/j.ejphar.2016.05.039
2015
Kaczara, P., Motterlini, R., Rosen, G.M., Augustynek, B., Bednarczyk, P., Szewczyk, A., Foresti, R., Chlopicki, S. Carbon monoxide released by CORM-401 uncouples mitochondrial respiration and inhibits glycolysis in endothelial cells: A role for mitoBKCa channels (2015) Biochimica et Biophysica Acta – Bioenergetics, 1847 (10), art. no. 47501, pp. 1297-1309. DOI: 10.1016/j.bbabio.2015.07.004
Laskowski, M., Kicinska, A., Szewczyk, A., Jarmuszkiewicz, W. Mitochondrial large-conductance potassium channel from Dictyostelium discoideum (2015) International Journal of Biochemistry and Cell Biology, 60, pp. 167-175. DOI: 10.1016/j.biocel.2015.01.006
2014
Olszewska, A., Bednarczyk, P., Siemen, D., Szewczyk, A. Modulation of the mitochondrial large-conductance calcium-regulated potassium channel by polyunsaturated fatty acids (2014) Biochimica et Biophysica Acta – Bioenergetics, 1837 (10), pp. 1602-1610. DOI: 10.1016/j.bbabio.2014.07.010
Augustynek, B., Kudin, A.P., Bednarczyk, P., Szewczyk, A., Kunz, W.S. Hemin inhibits the large conductance potassium channel in brain mitochondria: A putative novel mechanism of neurodegeneration (2014) Experimental Neurology, 257, pp. 70-75. DOI: 10.1016/j.expneurol.2014.04.022
Toczyłowska-Mamińska, R., Olszewska, A., Laskowski, M., Bednarczyk, P., Skowronek, K., Szewczyk, A. Potassium channel in the mitochondria of human keratinocytes (2014) Journal of Investigative Dermatology, 134 (3), pp. 764-772. DOI: 10.1038/jid.2013.422
2013
Bednarczyk, P., Wieckowski, M.R., Broszkiewicz, M., Skowronek, K., Siemen, D., Szewczyk, A. Putative Structural and Functional Coupling of the Mitochondrial BKCa Channel to the Respiratory Chain (2013) PLoS ONE, 8 (6), art. no. e68125, DOI: 10.1371/journal.pone.0068125
Bednarczyk, P., Koziel, A., Jarmuszkiewicz, W., Szewczyk, A. Large-conductance Ca2+-activated potassium channel in mitochondria of endothelial EA.hy926 cells (2013) American Journal of Physiology – Heart and Circulatory Physiology, 304 (11), pp. H1415-H1427. DOI: 10.1152/ajpheart.00976.2012
Olszewska, A., Szewczyk, A. Mitochondria as a pharmacological target: Magnum overview (2013) IUBMB Life, 65 (3), pp. 273-281. DOI: 10.1002/iub.1147
2012
Kajma, A., Szewczyk, A. A new pH-sensitive rectifying potassium channel in mitochondria from the embryonic rat hippocampus(2012) Biochimica et Biophysica Acta – Bioenergetics, 1817 (10), pp. 1867-1878. DOI: 10.1016/j.bbabio.2012.02.029
Wrzosek, A., Tomaskova, Z., Ondrias, K., Łukasiak, A., Szewczyk, A. The potassium channel opener CGS7184 activates Ca2 release from the endoplasmic reticulum (2012) European Journal of Pharmacology, 690 (1-3), pp. 60-67. DOI: 10.1016/j.ejphar.2012.06.029
Kulawiak, B., Szewczyk, A. Glutamate-induced cell death in HT22 mouse hippocampal cells is attenuated by paxilline, a BK channel inhibitor (2012) Mitochondrion, 12 (1), pp. 169-172. DOI: 10.1016/j.mito.2011.12.001
2011
Wieloch, W., Boguś, M.I., Ligeza, M., Koszela-Piotrowska, I., Szewczyk, A. Coronatin-1 isolated from entomopathogenic fungus Conidiobolus coronatus kills Galleria mellonella hemocytes in vitro and forms potassium channels in planar lipid membrane (2011) Toxicon, 58 (4), pp. 369-379. DOI: 10.1016/j.toxicon.2011.07.007
Matkovic, K., Koszela-Piotrowska, I., Jarmuszkiewicz, W., Szewczyk, A. Ion conductance pathways in potato tuber (Solanum tuberosum) inner mitochondrial membrane (2011) Biochimica et Biophysica Acta – Bioenergetics, 1807 (3), pp. 275-285. DOI: 10.1016/j.bbabio.2010.12.001
2010
Bednarczyk, P., Kowalczyk, J.E., Beresewicz, M., Dołowy, K., Szewczyk, A., Zabłocka, B. Identification of a voltage-gated potassium channel in gerbil hippocampal mitochondria (2010) Biochemical and Biophysical Research Communications, 397 (3), pp. 614-620. DOI: 10.1016/j.bbrc.2010.06.011
Kominkova, V., Malekova, L., Tomaskova, Z., Slezak, P., Szewczyk, A., Ondrias, K. Modulation of intracellular chloride channels by ATP and Mg2+ (2010) Biochimica et Biophysica Acta – Bioenergetics, 1797 (6-7), pp. 1300-1312. DOI: 10.1016/j.bbabio.2010.02.031
Szewczyk, A., Kajma, A., Malinska, D., Wrzosek, A., Bednarczyk, P., Zabłocka, B., Dołowy, K. Pharmacology of mitochondrial potassium channels: Dark side of the field (2010) FEBS Letters, 584 (10), pp. 2063-2069. DOI: 10.1016/j.febslet.2010.02.048
Malinska, D.*, Kulawiak, B.*, Wrzosek, A., Kunz, W.S., Szewczyk, A. The cytoprotective action of the potassium channel opener BMS-191095 in C2C12 myoblasts is related to the modulation of calcium homeostasis (2010) Cellular Physiology and Biochemistry, 26 (2), pp. 235-246. DOI: 10.1159/000320523
2009
Debska-Vielhaber, G., Godlewski, M.M., Kicinska, A., Skalska, J., Kulawiak, B., Piwonska, M., Zablocki, K., Kunz, W.S., Szewczyk, A., Motyl, T. Large-conductance K+ channel openers induce death of human glioma cells (2009) Journal of Physiology and Pharmacology, 60 (4), pp. 27-36.
Koszela-Piotrowska, I., Matkovic, K., Szewczyk, A., Jarmuszkiewicz, W. A large-conductance calcium-activated potassium channel in potato (Solanum tuberosum) tuber mitochondria (2009) Biochemical Journal, 424 (2), pp. 307-316. DOI: 10.1042/BJ20090991
Szewczyk, A., Jarmuszkiewicz, W., Kunz, W.S. Mitochondrial potassium channels (2009) IUBMB Life, 61 (2), pp. 134-143. DOI: 10.1002/iub.155
Choma, K., Bednarczyk, P., Koszela-Piotrowska, I., Kulawiak, B., Kudin, A., Kunz, W.S., Dołowy, K., Szewczyk, A. Single channel studies of the ATP-regulated potassium channel in brain mitochondria (2009) Journal of Bioenergetics and Biomembranes, 41 (4), pp. 323-334. DOI: 10.1007/s10863-009-9233-7
Skalska, J., Bednarczyk, P., Piwońska, M., Kulawiak, B., Wilczynski, G., Dołowy, K., Kudin, A.P., Kunz, W.S., Szewczyk, A. Calcium ions regulate K+ uptake into brain mitochondria: The evidence for a novel potassium channel (2009) International Journal of Molecular Sciences, 10 (3), pp. 1104-1120. DOI: 10.3390/ijms10031104
Wrzosek, A., Łukasiak, A., Gwóźdź, P., Malińska, D., Kozlovski, V.I., Szewczyk, A., Chlopicki, S., Dołowy, K. Large-conductance K+ channel opener CGS7184 as a regulator of endothelial cell function (2009) European Journal of Pharmacology, 602 (1), pp. 105-111. DOI: 10.1016/j.ejphar.2008.10.066
2008
Bednarczyk, P., Dołowy, K., Szewczyk, A. New properties of mitochondrial ATP-regulated potassium channels (2008) Journal of Bioenergetics and Biomembranes, 40 (4), pp. 325-335. DOI: 10.1007/s10863-008-9153-y
Kulawiak, B., Kudin, A.P., Szewczyk, A., Kunz, W.S. BK channel openers inhibit ROS production of isolated rat brain mitochondria (2008) Experimental Neurology, 212 (2), pp. 543-547. DOI: 10.1016/j.expneurol.2008.05.004
Skalska, J., Piwońska, M., Wyroba, E., Surmacz, L., Wieczorek, R., Koszela-Piotrowska, I., Zielińska, J., Bednarczyk, P., Dołowy, K., Wilczynski, G.M., Szewczyk, A., Kunz, W.S. A novel potassium channel in skeletal muscle mitochondria (2008) Biochimica et Biophysica Acta – Bioenergetics, 1777 (7-8), pp. 651-659. DOI: 10.1016/j.bbabio.2008.05.007
Piwonska, M., Wilczek, E., Szewczyk, A., Wilczynski, G.M. Differential distribution of Ca2+-activated potassium channel β4 subunit in rat brain: Immunolocalization in neuronal mitochondria (2008) Neuroscience, 153 (2), pp. 446-460. DOI: 10.1016/j.neuroscience.2008.01.050
2007
Kicinska, A., Swida, A., Bednarczyk, P., Koszela-Piotrowska, I., Choma, K., Dolowy, K., Szewczyk, A., Jarmuszkiewicz, W. ATP-sensitive potassium channel in mitochondria of the eukaryotic microorganism Acanthamoeba castellanii (2007) Journal of Biological Chemistry, 282 (24), pp. 17433-17441. DOI: 10.1074/jbc.M701496200
Kwiatkowska, K., Hordejuk, R., Szymczyk, P., Kulma, M., Abdel-Shakor, A.-B., Płucienniczak, A., Dołowy, K., Szewczyk, A., Sobota, A. Lysenin-His, a sphingomyelin-recognizing toxin, requires tryptophan 20 for cation-selective channel assembly but not for membrane binding (2007) Molecular Membrane Biology, 24 (2), pp. 121-134. DOI: 10.1080/09687860600995540
Malekova, L., Kominkova, V., Ferko, M., Stefanik, P., Krizanova, O., Ziegelhöffer, A., Szewczyk, A., Ondrias, K. Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart (2007) Biochimica et Biophysica Acta – Bioenergetics, 1767 (1), pp. 31-44. DOI: 10.1016/j.bbabio.2006.10.004
2006
Szewczyk, A., Skalska, J., Głab, M., Kulawiak, B., Malińska, D., Koszela-Piotrowska, I., Kunz, W.S. Mitochondrial potassium channels: From pharmacology to function (2006) Biochimica et Biophysica Acta – Bioenergetics, 1757 (5-6), pp. 715-720. DOI: 10.1016/j.bbabio.2006.05.002
Hordejuk, R., Szewczyk, A., Dołowy, K. The heterogeneity of ion channels in chromaffin granule membranes (2006) Cellular and Molecular Biology Letters, 11 (3), pp. 312-325. DOI: 10.2478/s11658-006-0027-1
2005
Skalska, J., Debska, G., Kunz, W.S., Szewczyk, A. Antidiabetic sulphonylureas activate mitochondrial permeability transition in rat skeletal muscle (2005) British Journal of Pharmacology, 145 (6), pp. 785-791. DOI: 10.1038/sj.bjp.0706214
Moghimi, S.M., Symonds, P., Murray, J.C., Hunter, A.C., Debska, G., Szewczyk, A. A two-stage poly(ethylenimine)-mediated cytotoxicity: Implications for gene transfer/therapy (2005) Molecular Therapy, 11 (6), pp. 990-995. DOI: 10.1016/j.ymthe.2005.02.010
Bednarczyk, P., Dołowy, K., Szewczyk, A. Matrix Mg2+ regulates mitochondrial ATP-dependent potassium channel from heart (2005) FEBS Letters, 579 (7), pp. 1625-1632. DOI: 10.1016/j.febslet.2005.01.077
Kulawiak B, Bednarczyk P. Reconstitution of brain mitochondria inner membrane into planar lipid bilayer (2005) Acta Neurobiol Exp (Wars). 65(3):271-6.
2004
Hordejuk, R., Lobanov, N.A., Kicinska, A., Szewczyk, A., Dolowy, K. pH modulation of large conductance potassium channel from adrenal chromaffin granules (2004) Molecular Membrane Biology, 21 (5), pp. 307-313. DOI: 10.1080/10647440400003899
Bednarczyk, P., Kicińska, A., Kominkova, V., Ondrias, K., Dolowy, K., Szewczyk, A. Quinine inhibits mitochondrial ATP-regulated potassium channel from bovine heart (2004) Journal of Membrane Biology, 199 (2), pp. 63-72. DOI: 10.1007/s00232-004-0676-9
Moghimi, S.M., Hunter, A.C., Murray, J.C., Szewczyk, A., Savić, R., Luo, L., Eisenberg, A., Maysinger, D. Cellular Distribution of Nonionic Micelles (2004) Science, 303 (5658), pp. 626-628. DOI: 10.1126/science.303.5658.626
Kicinska, A., Skalska, J., Szewczyk, A. Mitochondria and Big-Conductance Potassium Channel Openers (2004) Toxicology Mechanisms and Methods, 14 (1-2), pp. 63-65. DOI: 10.1080/15376520490257491
Kicinska, A., Szewczyk, A. Large-Conductance Potassium Cation Channel Opener NS1619 Inhibits Cardiac Mitochondria Respiratory Chain (2004) Toxicology Mechanisms and Methods, 14 (1-2), pp. 59-61. DOI: 10.1080/15376520490257482
2003
Debska, G., Kicinska, A., Dobrucki, J., Dworakowska, B., Nurowska, E., Skalska, J., Dolowy, K., Szewczyk, A. Large-conductance K+ channel openers NS1619 and NS004 as inhibitors of mitochondrial function in glioma cells (2003) Biochemical Pharmacology, 65 (11), pp. 1827-1834. DOI: 10.1016/S0006-2952(03)00180-1
2002
Debska, G., Kicinska, A., Skalska, J., Szewczyk, A., May, R., Elger, C.E., Kunz, W.S. Opening of potassium channels modulates mitochondrial function in rat skeletal muscle (2002) Biochimica et Biophysica Acta – Bioenergetics, 1556 (2-3), pp. 97-105. DOI: 10.1016/S0005-2728(02)00340-7
Szewczyk, A., Wojtczak, L. Mitochondria as a pharmacological target (2002) Pharmacological Reviews, 54 (1), pp. 101-127. DOI: 10.1124/pr.54.1.101
2001
Debska, G., May, R., Kicińska, A., Szewczyk, A., Elger, C.E., Kunz, W.S. Potassium channel openers depolarize hippocampal mitochondria (2001) Brain Research, 892 (1), pp. 42-50. DOI: 10.1016/S0006-8993(00)03187-5
Golczak, M., Kicinska, A., Bandorowicz-Pikula, J., Buchet, R., Szewczyk, A., Pikula, S. Acidic pH-induced folding of annexin VI is a prerequisite for its insertion into lipid bilayers and formation of ion channels by the protein molecules. (2001) The FASEB Journal, 15 (6), pp. 1083-1085. DOI: 10.1096/fj.00-0523fje
Mak, P., Szewczyk, A., Mickowska, B., Kicinska, A., Dubin, A. Effect of antimicrobial apomyoglobin 56-131 peptide on liposomes and planar lipid bilayer membrane (2001) International Journal of Antimicrobial Agents, 17 (2), pp. 137-142. DOI: 10.1016/S0924-8579(00)00328-9
1999
Szewczyk, A., Wójcik, G., Lobanov, N.A., Nalecz, M.J. Modification of the mitochondrial sulfonylurea receptor by thiol reagents (1999) Biochemical and Biophysical Research Communications, 262 (1), pp. 255-258. DOI: 10.1006/bbrc.1999.1190
Szewczyk, A., Marbán, E. Mitochondria: A new target for K+ channel openers (1999) Trends in Pharmacological Sciences, 20 (4), pp. 157-161. DOI: 10.1016/S0165-6147(99)01301-2