This web page is focused on MAESTRO project supported by National Science Center (2019/34/A/NZ1/00352)
Mitochondria provide cells with energy to carry out fundamental organism functions. Additionally, mitochondria are involved in such important phenomena as apoptosis, necrosis or aging. The proper functioning of mitochondria depends on the maintenance of transmembrane potential. One of the groups of proteins involved in ion transport are. potassium channels of the inner mitochondrial membrane. It has been shown that the activation of mitochondrial potassium channels in various cell types can lead to cell protection against damage, a phenomenon known as cytoprotection. The research project aims to identify new infrared light-induced cytoprotective mechanisms. Our initial studies suggests that mitochondrial potassium channels change their activity when exposed to infrared light.

Latest news

New Review on Mitochondrial Potassium Channels

Mitochondria play a crucial role in cytoprotection, cellular senescence, tumor metabolism, and inflammation. One of the key mechanisms regulating these processes is the transport of potassium ions across the inner mitochondrial membrane, mediated by specific potassium channels. The latest review article, Mitochondrial potassium channels: New properties and functions, published in Biochimica et Biophysica Acta (BBA) – Bioenergetics, …

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Two OPUS 27 grants awarded to our team!

We are thrilled to announce that the National Science Centre (NCN) has awarded two OPUS 27 grants, which will be conducted in collaboration with the Department of Physics and Biophysics, Institute of Biology, Warsaw University of Life Sciences-SGGW. Project 1: „Mitochondrial potassium channels as sensors and regulators of redox signaling”, PI dr hab. Bogusz Kulawiak …

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The 15th Annual WMS Meeting on Targeting Mitochondria

The 15th Annual WMS Meeting on Targeting Mitochondria, held October 29-31, 2024 in Berlin, Germany. 112 presentations presented innovative research and advances in mitochondrial science to 151 attendees from 41 countries. Poland was represented by 4 attendees from 3 different laboratories. The Intracellular Ion Channels Lab from the Nencki Institute was represented by Dr. Monika …

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