This web page is focused on MAESTRO project supported by National Science Center (2019/34/A/NZ1/00352)
Mitochondria provide cells with energy to carry out fundamental organism functions. Additionally, mitochondria are involved in such important phenomena as apoptosis, necrosis or aging. The proper functioning of mitochondria depends on the maintenance of transmembrane potential. One of the groups of proteins involved in ion transport are. potassium channels of the inner mitochondrial membrane. It has been shown that the activation of mitochondrial potassium channels in various cell types can lead to cell protection against damage, a phenomenon known as cytoprotection. The research project aims to identify new infrared light-induced cytoprotective mechanisms. Our initial studies suggests that mitochondrial potassium channels change their activity when exposed to infrared light.

Latest news

PhD Defense Successfully Completed at the Nencki Institute!

We are pleased to announce that on May 9th, 2025, Shur Karolina Gałecka successfully defended her PhD thesis entitled: „Mitochondrial large-conductance calcium-activated potassium channel – structure and interactions” The research was carried out at the Nencki Institute of Experimental Biology, Polish Academy of Sciences, in the Intracellular Ion Channels Laboratory under the supervision of Dr. …

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38th International Conference Bioenergetics

The 38th International Conference Bioenergetics took place on May 7–9, 2025, in Vysoké nad Jizerou, Czech Republic, and was organized by the Institute of Physiology of the Czech Academy of Sciences in Prague. The event was attended by Karolina Pytlak, Barbara Kalenik, Piotr Koprowski, and Bogusz Kulawiak. Barbara Kalenik and Karolina Pytlak presented their research …

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New Review on Mitochondrial Potassium Channels

Mitochondria play a crucial role in cytoprotection, cellular senescence, tumor metabolism, and inflammation. One of the key mechanisms regulating these processes is the transport of potassium ions across the inner mitochondrial membrane, mediated by specific potassium channels. The latest review article, Mitochondrial potassium channels: New properties and functions, published in Biochimica et Biophysica Acta (BBA) – Bioenergetics, …

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